Timeline Entry
@bilalissi
• 4 years ago
• comments: 0
My name IS BILALISSI. I'm a PhD student on poutry science et CERSA (Togo).I have 1 publication at Européen poultry science journal. Currently I'm Working on incubator CO2 level on embryo development
@ashutosh
• 4 years ago
• comments: 2
RESEARCH EXPERTISES
Expertise in drug development as well as in basic chemistry. This in details involves, all the organic syntheses, purification by recrystallization techniques, all the chromatography methods, NMR, IR, Mass spectroscopy, etc and its pharmacological evaluation against specific targets.
In pharmaceutical chemistry experienced in Molecular hybridization (MH) technique, used to combine two medicinally important scaffolds such as chromene (different benzopyrans /coumarins /flavones) and dihydropyrimidinone).
Utilized heterogeneous catalyst (SiW (H4W12SiO40), PMo (H3PMo12O40), SiMo (H4SiO4Mo12O36), PW (H3PW12O40)) in organic reactions.
In carbohydrate chemistry synthesis of natural molecule mimicking flavones-C-glycosides and coumarin-C-glycoside modulating traditional carbon-Ferrier rearrangement reaction altering it to one pot Mukaiyama type carbon Ferrier rearrangement reaction.
In natural product chemistry I have isolated different natural molecules such as Flavonoids, xanthones, triterpenes and seccoiridoids from the extracts of 5 different plants including Swertia angustifolia, Pinus gerardina, etc. Different techniques were used for the isolation such as Morphological/Anatomical Analysis, TLC/HPTLC analysis, HPLC Analysis, GC Analysis, Spectroscopic Methods: NMR/MS/NIR/FT-IR. Molecular Biological Methods. Natural product isolation (various Xanthones, Oleanolic acid, beta sitosterol, etc.) and semi-synthetic work on Swertia angustifolia.
Applying green chemistry I have developed a novel method for the synthesis of various chromene dihydropyrimidinone (CDHPM) molecules using recyclable Fe/Al pillared clay catalyst and studied their pharmacokinetic parameters like aqueous solubility, lipophilicity, P-glycoprotein (P-gp) dependent ATPase activity, permeability, plasma protein binding, red blood cell (RBC) partitioning, metabolic stability in liver microsomes and in-vitro-in-vivo computations. Also studied ligand interaction for those compounds with LYS 218 &GLN 220 of NF-kB (PDB: 1NF I) as target protein to study the interaction of DHPMs with the target protein.
Expertise in drug development as well as in basic chemistry. This in details involves, all the organic syntheses, purification by recrystallization techniques, all the chromatography methods, NMR, IR, Mass spectroscopy, etc and its pharmacological evaluation against specific targets.
In pharmaceutical chemistry experienced in Molecular hybridization (MH) technique, used to combine two medicinally important scaffolds such as chromene (different benzopyrans /coumarins /flavones) and dihydropyrimidinone).
Utilized heterogeneous catalyst (SiW (H4W12SiO40), PMo (H3PMo12O40), SiMo (H4SiO4Mo12O36), PW (H3PW12O40)) in organic reactions.
In carbohydrate chemistry synthesis of natural molecule mimicking flavones-C-glycosides and coumarin-C-glycoside modulating traditional carbon-Ferrier rearrangement reaction altering it to one pot Mukaiyama type carbon Ferrier rearrangement reaction.
In natural product chemistry I have isolated different natural molecules such as Flavonoids, xanthones, triterpenes and seccoiridoids from the extracts of 5 different plants including Swertia angustifolia, Pinus gerardina, etc. Different techniques were used for the isolation such as Morphological/Anatomical Analysis, TLC/HPTLC analysis, HPLC Analysis, GC Analysis, Spectroscopic Methods: NMR/MS/NIR/FT-IR. Molecular Biological Methods. Natural product isolation (various Xanthones, Oleanolic acid, beta sitosterol, etc.) and semi-synthetic work on Swertia angustifolia.
Applying green chemistry I have developed a novel method for the synthesis of various chromene dihydropyrimidinone (CDHPM) molecules using recyclable Fe/Al pillared clay catalyst and studied their pharmacokinetic parameters like aqueous solubility, lipophilicity, P-glycoprotein (P-gp) dependent ATPase activity, permeability, plasma protein binding, red blood cell (RBC) partitioning, metabolic stability in liver microsomes and in-vitro-in-vivo computations. Also studied ligand interaction for those compounds with LYS 218 &GLN 220 of NF-kB (PDB: 1NF I) as target protein to study the interaction of DHPMs with the target protein.
@dreng-osama
• 4 years ago
Asalam Alikom, I dr Osama Salem, Al-Azhar University, Northern Border University, College of Engineering, Civil Eng. Dept. Structure Division.
@marisen-mwale
• 5 years ago
• comments: 0
MARISEN MWALE : STATUS MARGINALIZATION THEORY
STATUS MARGINALIZATION: NEW SOCIAL THEORY BY MARISEN MWALE
#StatusMarginalization Social Theory: Case of Democracy not ideal for Utra-Poor Nations. Social Theory- By- Marisen Mwale The premise or logic behind this #Theory is...
@raghavparouha
• 5 years ago
• comments: 0
https://scholar.google.co.in/citations?user=talhHfQAAAAJ&hl=en,
Dr Raghav Prasad Parouha (Young Scientist)
Dr Raghav Prasad Parouha (Young Scientist)
@deivasigamani
• 5 years ago
• comments: 2
We need recent development of fish immunology and immune system in related to human life.